But I don't have any cells! What about viruses? What kind of codon usage patterns can viral genomes be expected to have? None? Phylogenetically conserved? (based on mutational bias of their polymerases) Adaptation to the host cell that they replicate in? Positively (for translational efficiency) or Negatively (to slow down translation)? Adoption of host's composition bias? What if they have more than one host?